Centre for Medical Radiation Physics (CMRP) is a research strength at the University of Wollongong, the main research theme of this centre is to develop prototype novel radiation dosimeters. Multiple detector systems have been developed by Prof Rosenfelds’ group for various radiation detector applications. This paper focuses on four current detector systems being developed and studied at CMRP. Two silicon array detectors include the magic plate and dose magnifying glass (DMG), the primary focus of these two detectors is high spatial and temporal resolution dosimetry in intensity modulated radiation therapy (IMRT) beams. The third detector discussed is the MOSkin which is a high spatial resolution detector based on MOSFET technology, its primary role is in vivo dosimetry. The fourth detector system discussed is BrachyView, this is a high resolution dose viewing system based on Medipix detector technology.