Utilising Cyclopropane Scaffolds in Synthetic Methodology and Syntheses of Prodrugs

The ring-opening process of cyclopropane derivatives is prominent in biological processes and synthetic methodology. The reactivity of bifunctional three-membered rings is attributed to the ring-strain and the attached functional groups which can stabilise their ring-opened counterparts. This thesis reports the use of cyclopropane derivatives in synthetic methodology and syntheses of prodrugs.