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Microglia activation impairs neurites and mitophagy associated with aging

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thesis
posted on 2024-11-12, 09:37 authored by Anjila Dongol
Alzheimer's disease (AD) is a degenerating neural connectivity disorder that results in memory loss and cognitive impairment. The accumulation of amyloid-β (Aβ) in the brain is the first pathological mechanism to initiate AD pathogenesis. However, the precise role of Aβ in the disease progression remains unclear. Thus, it is of high importance to determine the exact role of Aβ throughout the entire course of AD to treat or possibly prevent AD progression.

History

Year

2023

Thesis type

  • Doctoral thesis

Faculty/School

School of Medical, Indigenous and Health Sciences

Language

English

Disclaimer

Unless otherwise indicated, the views expressed in this thesis are those of the author and do not necessarily represent the views of the University of Wollongong.

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