University of Wollongong
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Towards soft robotic devices for site-specific drug delivery

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posted on 2024-11-16, 08:34 authored by Gursel AliciGursel Alici
Considerable research efforts have recently been dedicated to the establishment of various drug delivery systems (DDS) that are mechanical/physical, chemical and biological/molecular DDS. In this paper, we report on the recent advances in site-specific drug delivery (site-specific, controlled, targeted or smart drug delivery are terms used interchangeably in the literature, to mean to transport a drug or a therapeutic agent to a desired location within the body and release it as desired with negligibly small toxicity and side effect compared to classical drug administration means such as peroral, parenteral, transmucosal, topical and inhalation) based on mechanical/physical systems consisting of implantable and robotic drug delivery systems. While we specifically focus on the robotic or autonomous DDS, which can be reprogrammable and provide multiple doses of a drug at a required time and rate, we briefly cover the implanted DDS, which are well-developed relative to the robotic DDS, to highlight the design and performance requirements, and investigate issues associated with the robotic DDS. Critical research issues associated with both DDSs are presented to describe the research challenges ahead of us in order to establish soft robotic devices for clinical and biomedical applications.

Funding

ARC Centre of Excellence for Electromaterials Science

Australian Research Council

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History

Citation

Alici, G. (2015). Towards soft robotic devices for site-specific drug delivery. Expert Review of Medical Devices, 12 (6), 703-715.

Journal title

Expert Review of Medical Devices

Volume

12

Issue

6

Pagination

703-715

Language

English

RIS ID

103839

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