University of Wollongong
Browse

Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials

Download (253.57 kB)
journal contribution
posted on 2024-11-14, 14:32 authored by Timothy Boyle, John BremnerJohn Bremner, Jonathan A Coates, John Deadman, Paul KellerPaul Keller, Stephen PyneStephen Pyne, Kittiya Somphol
An efficient synthesis of two new N-acetyl-4’-arylphenylalanines is described together with their incorporation in to a number of cationic peptoid antibacterial agents, one of which had an MIC of 7.8 μg/mL against Staphylococcus aureus.

History

Citation

Boyle, T. P., Bremner, J. B., Coates, J. A., Deadman, J., Keller, P. A., Pyne, S. G. & Somphol, K. (2009). Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials. European Journal of Medicinal Chemistry, 44 (3), 1001-1009.

Journal title

European Journal of Medicinal Chemistry

Volume

44

Issue

3

Pagination

1001-1009

Publisher website/DOI

Language

English

RIS ID

30147

Usage metrics

    Categories

    Keywords

    CMMB

    Licence

    Copyright - All rights reserved

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC