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Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry

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posted on 2024-11-14, 14:35 authored by Jennifer BeckJennifer Beck, Rajesh Gupta, Thitima Urathamakul, Nyree L Williamson, Margaret SheilMargaret Sheil, Janice Aldrich-Wright, Stephen RalphStephen Ralph
ESI mass spectra show that up to five ruthenium molecules can bind non-covalently to double stranded 16mer DNA, and provide information on the relative affinity and DNA sequence selectivity of different ruthenium complexes.

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Citation

Beck, J. L., Gupta, R., Urathamakul, T., Williamson, N. L., Sheil, M., Aldrich-Wright, J. & Ralph, S. F. (2003). Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry. Chemical Communications, (5), 626-627.

Journal title

Chemical Communications

Volume

3

Issue

5

Pagination

626-627

Publisher website/DOI

Language

English

RIS ID

9957

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    Keywords

    massesispectrometryprobingrutheniumdnametallointercalatorsselectivityCMMB

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