Potential control of risperidone-related cognitive deficits by adjunctive aripiprazole treatment

We have read with great interest Uchida and colleagues’ paper in your journal (2009; 29: 571–576), which reported that a high dosage of risperidone had a negative impact on cognition in older patients with schizophrenia. This finding is consistent with that of a previous study of a younger patient group showing that schizophrenia patients under high antipsychotic dosage have poor cognitive function performance....