posted on 2024-11-16, 06:50authored byNeville J A Coughlan, Michael S Scholz, Christopher Hansen, Adam TrevittAdam Trevitt, Brian D Adamson, Evan J Bieske
A cationic degradation product, formed in solution from retinal Schiff base (RSB), is examined in the gas phase using ion mobility spectrometry, photoisomerization action spectroscopy, and collision induced dissociation (CID). The degradation product is found to be N-n-butyl-2-(β-ionylidene)-4-methylpyridinium (BIP) produced through 6π electrocyclization of RSB followed by protonation and loss of dihydrogen. Ion mobility measurements show that BIP exists as trans and cis isomers that can be interconverted through buffer gas collisions and by exposure to light, with a maximum response at λ = 420 nm.
Funding
Multiplexed capabilities for surface analysis and imaging by mass spectrometry
Coughlan, N. J. A., Scholz, M. S., Hansen, C. S., Trevitt, A. J., Adamson, B. D. & Bieske, E. J. (2016). Photo and collision induced isomerization of a cyclic retinal derivative: an ion mobility study. Journal of the American Society for Mass Spectrometry, 27 (9), 1483-1490.
Journal title
Journal of the American Society for Mass Spectrometry