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Opioid Agonist Treatment for Patients With Dependence on Prescription Opioids

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posted on 2024-11-14, 19:11 authored by Suzanne Nielsen, Briony LaranceBriony Larance, Nicholas Lintzeris
Clinical Question Are different opioid agonist treatments (eg, methadone vs buprenorphine) associated with differences in efficacy for treating prescription opioid dependence, and is long-term maintenance of opioid agonist treatment associated with differences in efficacy compared with opioid taper or psychological treatments alone? Bottom Line For patients who are dependent on prescription opioids, long-term maintenance of opioid agonists is associated with less prescription opioid use and better adherence to medication and psychological therapies for opioid dependence compared with opioid taper or psychological treatments alone. Methadone maintenance was not associated with differences in therapeutic efficacy compared with buprenorphine maintenance treatment. Evidence quality was low to moderate.

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Citation

Nielsen, S., Larance, B. & Lintzeris, N. (2017). Opioid Agonist Treatment for Patients With Dependence on Prescription Opioids. JAMA: Journal of the American Medical Association, 317 (9), 967-968.

Journal title

JAMA - Journal of the American Medical Association

Volume

317

Issue

9

Pagination

967-968

Language

English

RIS ID

131293

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