How to diagnose and manage resistant hypertension

The number of truly drug-resistant hypertensive patients is small if careful attention is paid to blood pressure measurement, lifestyle measures are instituted and treatment is adjusted as required. An effective drug combination for the treatment of resistant hypertension is an ACE inhibitor (or angiotensin II receptor blocker), a calcium channel blocker and a thiazide-like diuretic, with possibly the addition of a fourth drug.