University of Wollongong
Browse

HDR brachytherapy in vivo source position verification using a 2D diode array: A Monte Carlo study

Download (708.84 kB)
journal contribution
posted on 2024-11-15, 08:53 authored by Joel PoderJoel Poder, Dean CutajarDean Cutajar, Susanna GuatelliSusanna Guatelli, Marco PetaseccaMarco Petasecca, Andrew Howie, Joseph A Bucci, Anatoly RozenfeldAnatoly Rozenfeld
Purpose This study aims to assess the accuracy of source position verification during high‐dose rate (HDR) prostate brachytherapy using a novel, in‐house developed two‐dimensional (2D) diode array (the Magic Plate), embedded exactly below the patient within a carbon fiber couch. The effect of tissue inhomogeneities on source localization accuracy is examined. Method Monte Carlo (MC) simulations of 12 source positions from a HDR prostate brachytherapy treatment were performed using the Geant4 toolkit. An Ir‐192 Flexisource (Isodose Control, Veenendaal, the Netherlands) was simulated inside a voxelized patient geometry, and the dose deposited in each detector of the Magic Plate evaluated. The dose deposited in each detector was then used to localize the source position using a proprietary reconstruction algorithm. Results The accuracy of source position verification using the Magic Plate embedded in the patient couch was found to be affected by the tissue inhomogeneities within the patient, with an average difference of 2.1 ± 0.8 mm (k = 1) between the Magic Plate predicted and known source positions. Recalculation of the simulations with all voxels assigned a density of water improved this verification accuracy to within 1 mm. Conclusion Source position verification using the Magic Plate during a HDR prostate brachytherapy treatment was examined using MC simulations. In a homogenous geometry (water), the Magic Plate was able to localize the source to within 1 mm, however, the verification accuracy was negatively affected by inhomogeneities; this can be corrected for by using density information obtained from CT, making the proposed tool attractive for use as a real‐time in vivo quality assurance (QA) device in HDR brachytherapy for prostate cancer.

History

Citation

Poder, J., Cutajar, D., Guatelli, S., Petasecca, M., Howie, A., Bucci, J. & Rozenfeld, A. (2018). HDR brachytherapy in vivo source position verification using a 2D diode array: A Monte Carlo study. Journal of Applied Clinical Medical Physics, 19 (4), 163-172.

Journal title

Journal of Applied Clinical Medical Physics

Volume

19

Issue

4

Pagination

163-172

Language

English

RIS ID

128210

Usage metrics

    Categories

    Keywords

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC