DNA Hydrogel Fiber with Self-Entanglement Prepared by Using an Ionic Liquid
journal contribution
posted on 2024-11-16, 08:07 authored by CK Lee, Su Ryon Shin, S H Lee, J Jeon, Insuk So, T M Kang, Sun I Kim, J Y Mun, Sung-Sik Han, Geoffrey SpinksGeoffrey Spinks, Gordon WallaceGordon Wallace, Seon Jeong KimSpinning strands: A hydrogel fiber made entirely of DNA without any covalent cross-links, composed of intertwined toroid entanglements of flexible DNA strands (see scheme), was prepared by a one-step wet-spinning method with a hydrophilic ionic liquid as the condensing agent and coagulation solvent. The internal structure of the fiber was a disordered arrangement of strands with a B-DNA form. The fiber was also stable in various aqueous solutions.