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Antimalarial Activity of 2,4-Diaminopyrimidines

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posted on 2024-11-14, 15:50 authored by J Morgan, R Haritakul, Paul KellerPaul Keller
A series of 2,4- and 4,6-diaminopyrimidines were prepared and evaluated for their in vitro antimalarial activity. Of the 12 compounds tested 7 showed reasonable activity with 1 having a sub-micromolar IC50.

History

Citation

This article was originally published as Morgan, J, Haritakul, R & Keller, PA, Antimalarial Activity of 2,4-Diaminopyrimidines, Letters in Drug Design & Discovery, 5(4), 2008, 277-280. Original journal article available here

Journal title

Letters in Drug Design and Discovery

Volume

5

Issue

4

Pagination

277-280

Publisher website/DOI

Language

English

RIS ID

26381

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    Keywords

    Antimalarialdiaminopyrimidinestructure-activity relationshipCMMB

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    Copyright - All rights reserved

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