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Gene network analysis and design

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conference contribution
posted on 2024-11-14, 09:24 authored by Matthew Berryman, Andrew Allison, Derek Abbott
Gene networks are composed of many different interacting genes and gene products (RNAs and proteins). They can be thought of as switching regions in n-dimensional space or as mass-balanced signaling networks. Both approaches allow for describing gene networks with the limited quantitative or even qualitative data available. We show how these approaches can be used in modeling the apoptosis gene network that has a vital role in tumor development. The open question is whether engineering changes to this network could be used as a possible cancer treatment.

History

Citation

Berryman, M. J., Allison, A. Abbott, D. (2005). Gene network analysis and design. Biomedical Applications of Micro- and Nanoengineering (pp. 126-133).

Parent title

Proceedings of SPIE--the International Society for Optical Engineering

Volume

5651

Pagination

126-133

Language

English

RIS ID

42439

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