Development of hybrid systems for cell-mediated muscle regeneration: advanced electromaterials and wet-spun biodegradable fibers

In myo-dystrophic processes such as Duchenne muscular dystrophy (DMD), onset of disease pathology is associated with significant loss of regenerative precursor cells. In the face of such significant cell loss, it is likely that even with the rectification of the genetic defect, some measure of cell replacement therapy will still be required to replace the large amounts muscle tissues and precursors lost during the dystrophic process.