A novel route to copper(ii) detection using 'click' chemistry-induced aggregation of gold nanoparticles

Authors

Carol Hua, University of New South Wales
William H. Zhang, University of New South Wales
Swahnnya De Almeida, University of New South Wales
Simone Ciampi, University of New South WalesFollow
Danmar Gloria, University of New South Wales
Guozhen Liu, University of New South Wales
Jason Brian Harper, University of New South Wales
J Justin Gooding, University of New South WalesFollow

RIS ID

105089

Publication Details

Hua, C., Zhang, W. H., De Almeida, S. R. M., Ciampi, S., Gloria, D., Liu, G., Harper, J. B. & Gooding, J. Justin. (2012). A novel route to copper(ii) detection using 'click' chemistry-induced aggregation of gold nanoparticles. The Analyst, 137 (1), 82-86.

Abstract

A simple colorimetric method for the detection of copper ions in water is described. This method is based on the 'click' copper(i)-catalyzed azide-alkyne cycloaddition reaction and its use in promoting the aggregation of azide-tagged gold nanoparticles by a dialkyne cross-linker is described. Nanoparticle cross-linking, evidenced as a colour change, is used for the detection of copper ions. The lowest detected concentration by the naked eye was 1.8 μM, with the response linear with log(concentration) between 1.8-200 μM. The selectivity relative to other potentially interfering ions was evaluated.