Time-dependence in homogeneous catalysis. 1. Many enzymes display the hallmarks of time-dependent ("mechanical") catalysis. Nonbiological homogeneous catalysts are typically energy-dependent ("thermodynamic") catalysts
In this chapter we will examine the common properties of enzymes relative to their equivalent nonbiological homogeneous catalysts.We will show that the general properties of catalysis by enzymes are consistent with, and predictive of, a time-dependent (mechanical) catalytic action. Those of equivalent nonbiological catalysts are consistent with energy-dependent (thermodynamic) catalysis.