Year

1996

Degree Name

Doctor of Philosophy

Department

Department of Chemistry

Abstract

Electrospray mass spectrometry (ESI-MS) has been used to examine a range of intact monoclonal antibodies (MAbs), antibody fragments, chemically-modified fragments and a range of other chemically-modified peptides and proteins as part of a broader study aimed at establishing ESI-MS as a method for the characterisation of radioimmunoconjugates (ie. radiolabelled monoclonal antibodies).

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