Background: In Pakistan, the prevalence of Type 2 diabetes is high ranging from 7.6 % (5.2 million populations) to 11 % as compared to the prevalence rate of 8.3% in the world. The high prevalence of type 2 diabetes in the country has been attributed to high-risk factors such as lack of physical activity, unhealthy food and eating habits among the Pakistani population. Aims: The main aim of this study is to use the quantitative method to explore the association between illness and cultural beliefs, family and healthcare provider support and self-management behaviours of patients of type 2 diabetes in middle-aged population of Pakistan.Materials and Methods: The study will employ quantitative design method to allow for a more comprehensive approach to address a multifaceted problem. The quantitative design will use self-administered survey questionnaires to be provided to n=200 randomly selected patients from the Medical Centre of rural area of Abbottabad, Pakistanto acquire the basic knowledge about diabetes and to measure the association between illness and cultural beliefs and self-management behaviours in that population. Results: The quantitative study will acquire demographic information and the basic knowledge about diabetes, illness beliefs, family and social support and self-management activities in the middle-aged population of Pakistan.Conclusion: This study will help to improve the diabetes self-management approach in middle-aged population in rural area of Pakistan and will help to better understand the contextual determinants of behaviours for future development of culturally appropriate interventions to modify the illness beliefs and support of self-management activities.