Controlled oxidation of pyrroles: synthesis of highly functionalized γ-lactams

Authors

James Howard, University of Tasmania
Christopher Hyland, University of WollongongFollow
Jeremy Just, University of Tasmania
Jason A. Smith, University of Tasmania

RIS ID

77466

Publication Details

Howard, J., Hyland, C. J. T., Just, J. & Smith, J. A. (2013). Controlled oxidation of pyrroles: synthesis of highly functionalized γ-lactams. Organic Letters, 15 (7), 1714-1717.

Abstract

The oxidation of pyrroles usually leads to uncontrolled polymerization and decomposition. To overcome this problem, the controlled oxidation of substituted pyrroles with Dess-Martin periodinane is reported. This strategy yields a range of 5-aroyloxypyrrolinones.