Controlled oxidation of pyrroles: synthesis of highly functionalized γ-lactams
RIS ID
77466
Abstract
The oxidation of pyrroles usually leads to uncontrolled polymerization and decomposition. To overcome this problem, the controlled oxidation of substituted pyrroles with Dess-Martin periodinane is reported. This strategy yields a range of 5-aroyloxypyrrolinones.
Publication Details
Howard, J., Hyland, C. J. T., Just, J. & Smith, J. A. (2013). Controlled oxidation of pyrroles: synthesis of highly functionalized γ-lactams. Organic Letters, 15 (7), 1714-1717.