Title

Controlled oxidation of pyrroles: synthesis of highly functionalized γ-lactams

RIS ID

77466

Publication Details

Howard, J., Hyland, C. J. T., Just, J. & Smith, J. A. (2013). Controlled oxidation of pyrroles: synthesis of highly functionalized γ-lactams. Organic Letters, 15 (7), 1714-1717.

Abstract

The oxidation of pyrroles usually leads to uncontrolled polymerization and decomposition. To overcome this problem, the controlled oxidation of substituted pyrroles with Dess-Martin periodinane is reported. This strategy yields a range of 5-aroyloxypyrrolinones.

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Link to publisher version (DOI)

http://dx.doi.org/10.1021/ol400491p