Using a conventional, off-the-shelf digital single lens reflex camera and flashes, we were able to create high-resolution panoramas of stratigraphic profiles ranging from a single meter to over 5 m in both height and width at the Middle Stone Age site of PP5-6 at Pinnacle Point, Mossel Bay, South Africa. The final photomosaics are isoluminant, rectilinear, and have a pixel spatial resolution of 1 mm. Furthermore, we systematically color-corrected the raw imagery. This process standardized the colors seen across the photomosaics while also creating reproducible and meaningful colors for relative colorimetric analysis between photomosiacs. Here, we provide a detailed discussion about the creation and application of our photomosaics. In the first part of the paper, we examine the specific characteristics of modern digital single lens reflex (DSLR) cameras and lenses that were important to us in developing our methodology. We also provide a detailed discussion about how to reproduce the methodology in the field and to post-process the imagery. In the final section of the paper, we give several examples to show how we apply our photomosaics within an empirical 3D GIS database. These examples are provided to show how photographic data can be integrated with other digitally-captured data and used to study the relationships between the stratigraphic features seen in the photomosaics and the 3D distribution of excavated archaeological piece-plots, geochronological samples, and other kinds of geological samples.