Synthesis of (+)-(1R,2S,9S,9aR)-octahydro-1H-pyrrolo-[1,2-a]azepine-1,2,9-triol: a potential glycosidase inhibitor

Authors

Karl B. Lindsay, University of Wollongong
Stephen G. Pyne, University of WollongongFollow

RIS ID

11492

Publication Details

Lindsay, K. & Pyne, S. G. (2004). Synthesis of (+)-(1R,2S,9S,9aR)-octahydro-1H-pyrrolo-[1,2-a]azepine-1,2,9-triol: a potential glycosidase inhibitor. Tetrahedron, 60 (19), 4173-4176.

Abstract

The title compound was prepared as a potential glycosidase inhibitor. Key steps in the synthesis are vinyl epoxide aminolysis, ring-closing metathesis, cis-dihydroxylation and then ring closure.