Three-component mannich-like reaction of 2-aminoimidazole
A three-component reaction of 2-aminoimidazole with various aldehydes and amines is described that generates 4-substituted 2-aminoimidazoles containing a new chiral centre, a new CC bond and a new CN bond. The reactions can be conducted in water and require only sodium carbonate as reagent. CSIRO 2011.
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