Phytochemical studies on Stemona plants: isolation of new tuberostemonine and stemofoline alkaloids

Authors

Thanapat Sastraruji, University of WollongongFollow
Araya Jatisatienr, Chiang Mai University
Kritchaya Issakul, Chiang Mai University
Stephen G. Pyne, University of WollongongFollow
Alison T. Ung, University of WollongongFollow
Wilford Lie, University of WollongongFollow
Morwenna C. Baird, University of WollongongFollow

RIS ID

17522

Publication Details

Sastraruji, T., Jatisatienr, A., Issakul, K., Pyne, S. G., Ung, A. T., Lie, W. and Williams, M. C. (2006). Phytochemical studies on Stemona plants: isolation of new tuberostemonine and stemofoline alkaloids. Natural Product Communications, 1 (10), 813-818.

Abstract

Two new tuberostemonine alkaloids, tuberostemonine L (3) and tuberostemonine M (4) and a new stemofoline alkaloid, (3’S)-hydroxystemofoline (5), along with two known alkaloids, (2’S)-hydroxystemofoline (1) and neotuberostemonine (2) have been isolated from a root extract of an unidentified Stemona species (Stemona sp.). The structure and relative configuration of these new alkaloids has been determined by spectral data interpretation, while the 3’S configuration of 5 was determined from NMR analysis of its (R)- and (S)-Mosher esters.

Link to publisher version (URL)

Natural Product Communications