Title

Synthesis of some cyclic indolic peptoids as potential antibacterials

Document Type

Journal Article

Publication Date

October 2006

Publication Details

This article was originally published as: Au, VS, Bremner, JB, Coates, J, et al, Synthesis of some cyclic indolic peptoids as potential antibacterials, Tetrahedron, 2006, 62(40), 9373-9382. The original journal can be found here through Elsevier.

Abstract

The synthesis of cyclic peptoids containing an indole hydrophobic scaffold has been realised through the ring-closing metathesis of diallylated precursors. The precursors and their cyclic counterparts possessed poor antibacterial activity in contrast to previously reported cyclic peptoids containing hydrophobic scaffolds.