Acute poisoning accounts for 10-20% of acute medical admis- 5ion5 in the UK. There is wide geographical variation in the substances involved in poisoning. In the UK, paracetamol poisoning is common, but it accounts for only 7% of overdoses in the USA. Poisoning with tricyclic antidepressants (TeAs), selective serotonin re-uptake inhibitors (SSRls) and drugs of misuse is very common in the UK and USA. In Southeast Asio, pesticide ingestion is endemic, and constitutes the most common cause of death by poisoning_
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