Title

Soluble adhesion molecules and interleukin-2 receptor concentrations in patients with autoimmune chronic hepatitis

Document Type

Journal Article

RIS ID

62596

Publication Details

Simpson, K. J., Jones, A. L., Forbes, A. Hayes, P. C. (1995). Soluble adhesion molecules and interleukin-2 receptor concentrations in patients with autoimmune chronic hepatitis. European Journal of Gastroenterology and Hepatology, 7 (5), 455-460.

Abstract

To test the hypothesis that elevated serum levels of intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), (s)E-selectin, (s)P-selectin and soluble interleukin-2 receptor (sIL-2R) occur in patients with biochemically inactive autoimmune hepatitis (AICH) compared with controls. Such a finding would suggest continued immune activation, which in the long-term would contribute to the development of cirrhosis in such patients.



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