The Illawarra Health and Medical Research Institute is a partnership between the University of Wollongong and the South Eastern Sydney Illawarra Area Health Service. IHMRI's research focuses on health and medical issues that are common in the Illawarra region and is aimed at improving the health and well being of the local community. IHMRI's goal is to foster research collaboration through the IHMRI Research Network, creating a centre of excellence and innovation that represents the focal point of health and medical research in this region.
Papers from 2013
Cerium oxide nanoparticles: influence of the high-Z component revealed on radioresistant 9L cell survival under X-ray irradiation, Adam Briggs, stephanie corde, Sianne Oktaria, Ryan Brown, Anatoly B. Rosenfeld, Michael Lerch, Konstantin Konstantinov, and Moeava Tehei
A comparison of patient matched meibum and tear lipidomes, Simon H. Brown, Carolina M. E Kunnen, Eva Duchoslav, Naveen K. Dolla, Michael J. Kelso, Eric B. Papas, Percy Lazon de la Jara, Mark D.P Willcox, Stephen J. Blanksby, and Todd W. Mitchell
Benefits, issues, and recommendations for personalized medicine in oncology in Canada, C Butts, S Kamel-Reid, G Batist, S Chia, C Blanke, M Moore, M B. Sawyer, C Desjardins, A Dubois, J Pun, K Bonter, and F D. Ashbury
Author reply, John Carmody, Victoria Traynor, Don C. Iverson, and Elena M. Marchetti
Novel behavioural characteristics of the APPSwe/PS1ΔE9 transgenic mouse model of Alzheimer's disease, David Cheng, Warren Logge, Jac Kee Low, Brett Garner, and Tim Karl
Potential value and limitation of dual inhibitors of pi3k and mtor in the treatment of cancer, Jiezhong Chen
Recent advance in the studies of beta-glucans for cancer therapy, Jiezhong Chen
The key regulatory roles of the PI3K/Akt signaling pathway in the functionalities of mesenchymal stem cells and applications in tissue regeneration, Jiezhong Chen, Ross Crawford, Chen Chen, and Yin Xiao
Vertical inhibition of the PI3K/Akt/mTOR pathway for the treatment of osteoarthritis, Jiezhong Chen, Ross Crawford, and Yin Xiao
Applications of nanotechnology for melanoma treatment, diagnosis, and theranostics, Jiezhong Chen, Renfu Shao, Xu Dong Zhang, and Chen Chen
The application of fungal beta-glucans for the treatment of colon cancer, Jiezhong Chen, Xu Dong Zhang, and Zhengyi Jiang
Estrogen-induced cholestasis: pathogenesis and therapeutic implications, Jiezhong Chen, Kong-nan Zhao, and Guang Bin Liu
Effects of antipsychotic medications on appetite, weight, and insulin resistance, Chao Deng
Mapping the pathophysiology of schizophrenia: interactions between multiple cellular pathways, Chao Deng and Brian Dean
Central administration of palmitic acid increases food intake and body temperature in male Sprague Dawley rats, Chi H. L Dinh, Alexander M. Szabo, Hongqin Wang, Yinghua Yu, and Xu-Feng Huang
Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1, Thomas Durek, Irina Vetter, C-I Anderson Wang, Leonid Motin, Oliver Knapp, David J. Adams, Richard J. Lewis, and Paul F. Alewood
Improving services for people with personality disorders: views of experienced clinicians, Mahnaz Fanaian, Kate L. Lewis, and Brin F. S Grenyer
Diastolic function is a strong predictor of mortality in patients with chronic kidney disease, Ahmad Farshid, Rajeev Pathak, Bruce Shadbolt, Leonard F. Arnolda, and Girish Talaulikar
Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia, S Fillman, N Cloonan, V S. Catts, L C. Miller, J Wong, T Mccrossin, M Cairns, and C S. Weickert
An audit of vending machines in public places in regional NSW, Australia, V Flood, A Carrad, A Alshukri, J Louie, B Kelly, H Yeatman, and L Tapsell
An audit of vending machines in public places in regional NSW, Australia, V Flood, A Carrad, A Alshukri, J Louie, B Kelly, H Yeatman, and L Tapsell
Rho/ROCK pathway is essential to the expansion, differentiation, and morphological rearrangements of human neural stem/progenitor cells induced by lysophosphatidic acid, Frisca Frisca, Duncan E. Crombie, Mirella Dottori, Yona Goldshmit, and Alice Pebay
Laparoscopic management of an adnexal mass during the second trimester of pregnancy, C Georgiou
Laparoscopy for theatre nurses, C Georgiou
Pregnancies following the use of balloon tamponade technology in the previous pregnancy, C Georgiou
Subsequent management of unsuccessful Fulshi clip tubal occlusion, C Georgiou
Intercellular propagated misfolding of wild-type Cu-Zn superoxide dismutase, Leslie I. Grad, Justin J. Yerbury, Bradley J. Turner, Will C. Guest, Eddie Pokrishevsky, Megan A. O'Neill, Anat Yanai, Judith M. Silverman, Rafaa Zeineddine, Lisa Corcoran, Janet R. Kumita, Leila Luheshi, Masoud Yousefi, Bradley M. Coleman, Andrew F. Hill, Steven S. Plotkin, and Neil R. Cashman
Neural correlates of successful encoding in schizophrenia: an event-related potential study, Amity Green, Paul Fitzgerald, Patricia T. Michie, Pradeep Nathan, and Rodney J. Croft
Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors, Anton A. Grishin, Hartmut Cuny, Andrew Hung, Richard J. Clark, Andreas Brust, Kalyana Akondi, Paul F. Alewood, David J. Craik, and David J. Adams
High-dose mushroom increases hepatic accumulation of triacylglycerol in rats fed with high-fat diet, D Handayani, B Meyer, J Chen, S Brown, T Mitchell, and Xu-Feng Huang
Structure-informed design of an enzymatically inactive vaccine component for group A Streptococcus, Anna Henningham, Daniel J. Ericsson, Karla Langer, Lachlan W. Casey, Blagojce Jovcevski, G S. Chhatwal, John Andrew Aquilina, Michael R. Batzloff, Bostjan Kobe, and Mark J. Walker
Regulator of G-protein signaling 5 controls blood pressure homeostasis and vessel wall remodeling, Vasyl Holobotovskyy, Mitali Manzur, Marianne Tare, Jennifer Burchell, Erin Bolitho, Helena Viola, Livia C. Hool, Leonard F. Arnolda, Douglas J. McKitrick, and Ruth Ganss
Age-dependent racemization of serine residues in a human chaperone protein, Michelle Y. S Hooi, Mark J. Raftery, and Roger J. W Truscott
Accelerated aging of Asp 58 in aA crystallin and human cataract formation, Michelle Yu Sung Hooi, Mark Raftery, and Roger J. Truscott
Interconversion of the peptide isoforms of aspartate: Stability of isoaspartates, Michelle Yu Sung Hooi, Mark Raftery, and Roger J. Truscott
Association between DBH 19bp insertion/deletion polymorphism and cognition in first-episode schizophrenic patients, Li Hui, Xuan Zhang, Ya Qin Yu, Mei Han, Xu-Feng Huang, Da Chun Chen, Zhi Ren Wang, Wei Li Du, Chang Gui Kou, Qiong Yu, Thomas R. Kosten, and Xiang Yang Zhang
The role of assertiveness on telephone crisis supporter well-being and service provision, Tara Hunt, Coralie Wilson, Peter Caputi, Alan Woodward, Grahame Gould, and Taneile Kitchingman
Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors, Marco C. Inserra, Shiva N. Kompella, Irina Vetter, Andreas Brust, Norelle L. Daly, Hartmut Cuny, David J. Craik, Paul F. Alewood, David J. Adams, and Richard J. Lewis
In vivo pharmacological evaluations of novel olanzapine analogues in rats: a potential new avenue for the treatment of schizophrenia, Somayeh Jafari, Xu-Feng Huang, Jessica L. Andrews, and Francesca Fernandez-Enright
Lipid Anti-Lipid Antibody Responses Correlate with Disease Activity in Systemic Lupus Erythematosus, Vojislav Jovanovic, Nurhuda Abdul Aziz, Yan Ting Lim, Amanda Ng Ai Poh, Sherlynn Jin Hui Chan, Eliza Ho Xin Pei, Fei Chuin Lew, Guanghou Shui, Andrew M. Jenner, Li Bowen, Eoin F. McKinney, Paul A. Lyons, Michael D. Kemeny, Kenneth G.C. Smith, Markus R. Wenk, and Paul A. MacAry
Are nicotinic acetylcholine receptors coupled to G proteins?, Nadine Kabbani, Jacob C. Nordman, Brian A. Corgiat, Daniel P. Veltri, Amarda Shehu, Victoria A. L Seymour, and David J. Adams
From the city to the bush: Increases in patient co-payments for medicines have impacted on medicine use across Australia, Anna Kemp, John Glover, David B. Preen, Max Bulsara, James Semmens, and Elizabeth Roughead
Impact of cost of medicines for chronic conditions on low income households in Australia, Anna Kemp, David B. Preen, John Glover, James Semmens, and Elizabeth E. Roughead
Myocardial infarction after intravitreal vascular endothelial growth factor inhibitors: A whole population study, Anna Kemp, David B. Preen, Nigel Morlet, Antony Clarke, Ian L. McAllister, Tom Briffa, Frank M. Sanfilippo, Jonathon Q. Ng, Charlotte McKnight, Wayne Reynolds, and Mark C. Gilles
Ascertaining invasive breast cancer cases; the validity of administrative and self-reported data sources in Australia, Anna Kemp, David B. Preen, Christobel Saunders, C D'Arcy J. Holman, Max Bulsara, Kris Rogers, and Elizabeth E. Roughead
The effect of a western diet on the synthesis and metabolism of cholesterol in the brain, F Kreilaus and A M. Jenner
The MASCC/ISOO Mucositis Guidelines: dissemination and clinical impact, Rajesh V. Lalla and Fredrick D. Ashbury
Mammalian expression systems and transfection techniques, Daunia Laurenti and Lezanne Ooi
Effects of olanzapine and betahistine co-treatment on serotonin transporter, 5-HT2A and dopamine D2 receptor binding density, Jiamei Lian, Xu-Feng Huang, Nagesh Pai, and Chao Deng
Deletion of ABCA7 increases cerebral amyloid-β deposition in the J20 mouse model of Alzheimer's disease, H Li, W S. Kim, K Ruberu, S Chan, D Elliott, J K. Low, D Cheng, T Karl, and B Garner
Whole grains, type 2 diabetes, coronary heart disease, and hypertension: links to the aleurone preferred over indigestible fiber, Stephen Lillioja; Andrew L. Neal; Linda Tapsell; and David R. Jacobs, Jr
Reciprocity as deliberative capacity: lessons from a citizens deliberation on carbon pricing mechanisms in Australia, Alex Y. Lo, Kim S. Alexander, Wendy Proctor, and Anthony Ryan
Sleep-wake behaviour and the EEG in altered states of consciousness, Sarah P. Loughran, Sabine Regel, Lilith Buetler, Martin Wieser, Robert Riener, and Peter Achermann
Characterization of the venom from the Australian scorpion Urodacus yaschenkoi: molecular mass analysis of components, cDNA sequences and peptides with antimicrobial activity, Karen S. Luna Ramirez, Veronica Quintero-Hernandez, Leonel Vargas-Jaimes, Cesar V. F Batista, Kenneth D. Winkel, and Lourival D. Possani
Age-dependent modification of proteins: N-terminal racemization, Brian Lyons, A H. Kwan, Joanne Jamie, and Roger J.W Truscott
An objective index of walkability for research and planning in the Sydney Metropolitan Region of New South Wales, Australia: an ecological study, Darren J. Mayne, Geoffrey Morgan, Alan Willmore, Nectarios Rose, Bin Jalaludin, Hilary Bambrick, and Adrian Bauman
Analysis of the psychological impact of a vascular risk factor intervention: results from a cluster randomized controlled trial in Australian general practice, Suzanne Helen Mckenzie, Upali W. Jayasinghe, Mahnaz Fanaian, Megan Passey, and Mark Fort Harris
Molecular markers for the study of streptococcal epidemiology, David J. McMillan, Martina L. Sanderson-Smith, Pierre Robert Smeesters, and Kadaba S. Sriprakash
Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding, M K. Montgomery, N L. Hallahan, S H. Brown, M Liu, T W. Mitchell, G J. Cooney, and N Turner
Evaluating success in public Health advocacy strategies, Michael Moore, Heather Yeatman, and Christina Pollard
An in vitro model of developmental synaptogenesis using cocultures of human neural progenitors and cochlear explants, Bryony A. Nayagam, Albert Edge, Karina Needham, Tomoko Hyakumura, Jessie Leung, David A. X Nayagam, and Mirella Dottori
Metabotropic glutamate receptor 5 in schizophrenia: emerging evidence for the development of antipsychotic drugs, Kelly A. Newell
Proenergetic effects of resveratrol in the murine neuronal cell line Neuro2a, Nhu T.Q Nguyen, Lezanne Ooi, Sabine C. Piller, and Gerald Munch
Characterization of forebrain neurons derived from late-onset Huntington's disease human embryonic stem cell lines, Jonathan C. Niclis, Anita Pinar, John M. Haynes, Walaa Alsanie, Robert Jenny, Mirella Dottori, and David S. Cram
Development and evaluation of the REACH (Recognise End of life And Care Holistically) out in Dementia toolkit, J. Potter, Ramesh Fernando, and Nancy Humpel
Categorising foods in terms of nutrient content, Yasmine Probst, Linda Tapsell, Rebecca Thorne, and Jane O'Shea
Genome-wide association analysis identifies 13 new risk loci for schizophrenia, Stephan Ripke, Colm O'Dushlaine, Kimberly Chambert, Jennifer L. Moran, Anna K. Kahler, Susanne Akterin, Sarah E. Bergen, Ann L. Collins, James J. Crowley, and Sibylle G. Schwab
Characterization of cholinesterases in the damselfish Sergeant major (Abudefduf saxatilis), Gabriela Rodriguez-Fuentes, Melina Soto, and Karen S. Luna Ramirez
A key role for the urokinase plasminogen activator (uPA) in invasive Group A streptococcal infection, Martina L. Sanderson-Smith, Yueling Zhang, Diane Ly, Deborah Donahue, Andrew Hollands, Victor Nizet, Marie Ranson, Victoria A. Ploplis, Mark J. Walker, and Francis J. Castellino
Association of rs1344706 in the ZNF804A gene with schizophrenia in a case/control sample from Indonesia, Sibylle G. Schwab, Agung A.A.A Kusumawardhani, Nan Dai, Wenwen Qin, Mutiara D.B Wildenauer, Feranindhya Agiananda, Nurmiati Amir, Ronald Antoni, Tiana Arsianti, Asmarahadi Asmarahadi, Hervita Diatri, Prianto Djatmiko, Irmansyah Irmansyah, Siti Khalimah, Irmia Kusumadewi, Profitasari Kusumaningrum, Petrin R. Lukman, Lukman Mustar, Martina W. Nasrun, Safyuni Naswati, Prasetiyawan Prasetiyawan, Gerald M. Semen, Kristiana Siste, Heriani Tobing, Natalia Widiasih, Tjhin Wiguna, Widayanti Dewi Wulandari, - Indonesian Schizophrenia Genetics Consortium, Beben Benyamin, and Dieter B. Wildenauer
Genetics of psychiatric disorders in the GWAS era: an update on schizophrenia, Sibylle G. Schwab and Dieter B. Wildenauer
Improved GC-MS methods for analysis of homocysteine, methionine and methylmalonate in cultured cells, A S. Spiro, A M. Jenner, and B Garner
Banking human induced pluripotent stem cells: lessons learned from embryonic stem cells?, Glyn N. Stacey, Jeremy M. Crook, Derek Hei, and Tenneille Ludwig
Preventing help-negation for suicidal ideation: Implications for thwarted belongingness, social network size and frequency of social interaction, Alexander Svenson, Coralie J. Wilson, and Peter Caputi
Age-related human nuclear cataract. Blindness due to inexorable protein deterioration, R Truscott
Discovering the cause of human age-related cataract, Roger JW Truscott, Michael Friedrich, Michelle Hooi, and Brian Lyons
Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus, James A. Tsatsaronis, Andrew Hollands, Jason N. Cole, Peter G. Maamary, Christine M. Gillen, Nouri L. Ben Zakour, Malak Kotb, Victor Nizet, Scott A. Beatson, Mark J. Walker, and Martina L. Sanderson-Smith
Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors, Bianca J. van Lierop, Samuel D. Robinson, Shiva N. Kompella, Alessia Belgi, Jeffrey R. McArthur, Andrew Hung, Christopher A. Macraild, David J. Adams, Raymond Norton, and Andrea J. Robinson
Recent highlights in the development of isatin-based anticancer agents, Kara L. Vine, Lidia Matesic, Julie M. Locke, and Danielle Skropeta
Rapid quantification of free cholesterol in tears using direct insertion/electron ionization-Mass spectrometry, Xiaojia Eric Wei, John Korth, Simon H. J Brown, Todd W. Mitchell, Roger J. W Truscott, Stephen J. Blanksby, Mark D. P Willcox, and Zhenjun Zhao
Cognitive, affective and social processes involved in help-negation after critical suicidal thoughts, Coralie Wilson, Alexander Svenson, and Peter Caputi
The association between overcommitment to work and depressive symptoms is moderated by the polymorphic region of the 5-HTT gene, Petra H. Wirtz, Johannes Siegrist, Anna Schuhmacher, Susanne Hoefels, Wolfgang Maier, Gregor Domes, Sibylle G. Schwab, and Astrid W. Zobel
Neurotrophin signaling and Alzheimer's Disease neurodegeneration - Focus on BDNF/TrkB signaling, Jenny Wong
Expression of NPAS3 in the human cortex and evidence of its posttranscriptional regulation by miR-17 during development, with implications for schizophrenia, Jenny Wong, Carlotta E. Duncan, Natalie J. Beveridge, Maree J. Webster, Murray J. Cairns, and Cynthia Shannon Weickert
Increases in two truncated TrkB isoforms in the prefrontal cortex of people with schizophrenia, Jenny Wong, D A Rothmond, M J Webster, and Cynthia Shannon Weickert
Reduction of histamine H1 receptor binding induced by high-fat diet can be prevented by DHA and dietary fiber in specific brain areas of male rats, Zhixiang Wu, Yinghua Yu, Yizhen Wu, Craig S. Patch, Alexander Szabo, and Xu-Feng Huang
Kv3.1 channels stimulate adult neural precursor cell proliferation and neuronal differentiation, Takahiro Yasuda, Hartmut Cuny, and David J. Adams
Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells, Meihua Yu, Siddharth Jambhrunkar, Peter Thorn, Jiezhong Chen, Wenyi Gu, and Chengzhong Yu
Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor, Rilei Yu, Shiva N. Kompella, David J. Adams, David J. Craik, and Quentin Kaas
DHA prevents altered 5-HT1A, 5-HT2A, CB1 and GABAA receptor binding densities in the brain of male rats fed a high-saturated-fat diet, Yinghua Yu, Yizhen Wu, Craig Patch, Zhixiang Wu, Alexander Szabo, Duo Li, and Xu-Feng Huang
Teasaponin reduces inflammation and central leptin resistance in diet-induced obese male mice, Yinghua Yu, Yizhen Wu, Alexander Szabo, Zhixiang Wu, Hongqin Wang, Duo Li, and Xu-Feng Huang
Development of subcellular fractionation techniques to determine the intracellular cobalamin transit in vitro and the impact of lysosomal dysfunction, H Zhao, K R. Ruberu, H Y. Li, and B Garner
Analysis of subcellular [57Co] cobalamin distribution in SH-SY5Y neurons and brain tissue, Hua Zhao, Kalani Ruberu, Hongyun Li, and Brett Garner
Papers from 2012
Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (CaV2.2) calcium channels, David J. Adams, Brid P. Callaghan, and Géza Berecki
Using a social functionalist framework to understand responses to projected sea level rise and managed retreat policies in Australia, Kim Alexander and Anthony Ryan
Managed retreat of coastal communities: understanding responses to projected sea level rise, Kim S. Alexander, Anthony Ryan, and Thomas G. Measham
Where to draw the line: understanding responses of Australian coastal communities to sea level rise adaptation policies, K S. Alexander, A Ryan, R Gorddard, R Wise, and A Leitch
Two-year course of cognitive function and mood in adults with congestive heart failure and coronary artery disease: The Heart-Mind Study, Osvaldo P. Almeida, Christopher Etherton-Beer, Nicola Lautenschlager, Leonard F. Arnolda, Helman Alfonso, and Leon Flicker