Title

Gating currents associated with sodium and calcium currents in an Aplysia neuron

RIS ID

106311

Publication Details

Adams, D. J. & Gage, P. W. (1976). Gating currents associated with sodium and calcium currents in an Aplysia neuron. Science, 192 (4241), 783-784.

Abstract

In a voltage-clamped aplysia neuron (R15), depolarization beyond -30 millivolts produces an inward sodium current. Depolarization beyond -10 millivolts produces an additional inward calcium current with slower kinetics than the sodium current. When these ionic currents have been suppressed and capacitive currents subtracted out, a small outward displacement current can be seen with depolarizations beyond -30 millivolts. An additional, slower displacement current is seen with depolarizations beyond -10 millivolts. The currents have an exponential decay with an increase in rate per 10°C increase in temperature of about 3 and are thought to be sodium and calcium gating currents.

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Link to publisher version (DOI)

http://dx.doi.org/10.1126/science.1265479