Gating currents associated with sodium and calcium currents in an Aplysia neuron

Authors

David J. Adams, University of New South WalesFollow
Peter W. Gage, University of New South Wales

RIS ID

106311

Publication Details

Adams, D. J. & Gage, P. W. (1976). Gating currents associated with sodium and calcium currents in an Aplysia neuron. Science, 192 (4241), 783-784.

Abstract

In a voltage-clamped aplysia neuron (R15), depolarization beyond -30 millivolts produces an inward sodium current. Depolarization beyond -10 millivolts produces an additional inward calcium current with slower kinetics than the sodium current. When these ionic currents have been suppressed and capacitive currents subtracted out, a small outward displacement current can be seen with depolarizations beyond -30 millivolts. An additional, slower displacement current is seen with depolarizations beyond -10 millivolts. The currents have an exponential decay with an increase in rate per 10°C increase in temperature of about 3 and are thought to be sodium and calcium gating currents.