Potential value and limitation of dual inhibitors of pi3k and mtor in the treatment of cancer

RIS ID

78982

Publication Details

Chen, J. (2013). Potential value and limitation of dual inhibitors of pi3k and mtor in the treatment of cancer. Current Cancer Drug Targets, 13 (2), 117-120.

Abstract

The critical roles of the phosphoinositied 3-kinase (PI3K) pathway in many cancers have been extensively studied and reviewed. Activation of the pathway has been associated with carcinogenesis, cancer maintenance and drug resistance.

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