The Illawarra Health and Medical Research Institute is a partnership between the University of Wollongong and the South Eastern Sydney Illawarra Area Health Service. IHMRI's research focuses on health and medical issues that are common in the Illawarra region and is aimed at improving the health and well being of the local community. IHMRI's goal is to foster research collaboration through the IHMRI Research Network, creating a centre of excellence and innovation that represents the focal point of health and medical research in this region.

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Papers from 2014

Altered ceramide acyl chain length and ceramide synthase gene expression in Parkinson's disease, Sarah Abbott, Hongyun Li, Sonia Sanz Munoz, Bianca Knoch, Marijka Batterham, Karen E. Murphy, Glenda M. Halliday, and Brett Garner

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Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism, Archana Bhaskaracharya, Phuong Dao-Ung, Iman Jalilian, Mari Spildrejorde, Kristen K. Skarratt, Stephen Fuller, Ronald Sluyter, and Leanne Stokes

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Trust, continuity and agency: keys to understanding older patients' attitudes to general practice trainees, Andrew Bonney, Sandra C. Jones, Donald C. Iverson, and Christopher Magee

Novel behavioural characteristics of female APPSwe/PS1ΔE9 double transgenic mice, David Cheng, Jac Kee Low, Warren Logge, Brett Garner, and Tim Karl

The role of Src in colon cancer and its therapeutic implications, Jiezhong Chen, Aymen Elfiky, Mei Han, Chen Chen, and M Wasif Saif

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Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways, Jiezhong Chen, Renfu Shao, Li Li, Zhi Ping Xu, and Wenyi Gu

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Insulin induces drug resistance in melanoma through activation of the PI3K/Akt pathway, Mengna Chi, Yan Ye, Xu Dong Zhang, and Jiezhong Chen

Site-restricted plasminogen activation mediated by group A streptococcal streptokinase variants, Simon M. Cook, Amanda Skora, Mark J. Walker, Martina L. Sanderson-Smith, and Jason D. McArthur

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Expression and purification of chaperone-active recombinant clusterin, Rebecca Dabbs and Mark R. Wilson

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Novel implications of Lingo-1 and its signaling partners in schizophrenia, F Fernandez-Enright, J L. Andrews, K A. Newell, C Pantelis, and Xu-Feng Huang

Detection, quantification, and total synthesis of novel 3-hydroxykynurenine glucoside-derived metabolites present in human lenses, Nicholas A. Gad, Jasminka Mizdrak, David I. Pattison, Michael J. Davies, Roger J. W Truscott, and Joanne F. Jamie

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Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms, Leslie I. Grad, Justin J. Yerbury, Bradley J. Turner, William C. Guest, Edward Pokrishevsky, Megan A. O'Neill, Anat Yanai, Judith M. Silverman, Rafaa Zeineddine, Lisa Corcoran, Janet Kumita, Leila Luheshi, Masoud Yousefi, Bradley M. Coleman, Andrew Hill, Steven S. Plotkin, Ian R. Mackenzie, and Neil R. Cashman

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Determination of anti-inflammatory activities of standardised preparations of plant- and mushroom-based foods, Dhanushka Gunawardena, Kirubakaran Shanmugam, Suresh Govindaraghavan, Mitchell Low, Louise Bennett, Richard Head, Lezanne Ooi, and Gerald Münch

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A high-dose Shiitake mushroom increases hepatic accumulation of triacylglycerol in rats fed a high-fat diet: underlying mechanism, Dian Handayani, Barbara J. Meyer, Jiezhong Chen, Simon H. J Brown, Todd W. Mitchell, and Xu-Feng Huang

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Dyslipidemia awareness, treatment, control and influence factors among adults in the Jilin province in China: a cross-sectional study, Huan He, Yaqin Yu, Yong Li, Chang Gui Kou, Bo Li, Yuchun Tao, Qing Zhen, Chang Wang, Joseph Sam Kanu, Xu-Feng Huang, Mei Han, and Yawen Liu

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Hypothalamic histamine H1 receptor-AMPK signaling time-dependently mediates olanzapine-induced hyperphagia and weight gain in female rats, Meng He, Qingsheng Zhang, Chao Deng, Hongqin Wang, Jiamei Lian, and Xu-Feng Huang

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Informal mining in livelihood diversification: mineral dependence and rural communities in Lao PDR, Kuntala Lahiri-Dutt, Kim Alexander, and Chansouk Insouvanh

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Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing, Diane Ly, Jude Taylor, James A. Tsatsaronis, Mercedes M. Monteleone, Amanda Skora, Cortny A. Donald, Tracy A. Maddocks, Victor Nizet, Nicholas P. West, Marie Ranson, Mark J. Walker, Jason D. McArthur, and Martina L. Sanderson-Smith

Separate mechanisms for age-related truncation and racemisation of peptide-bound serine, Brian Lyons, Joanne F. Jamie, and Roger J.W Truscott

Characterisation of a novel UV filter in the lens of the thirteen-lined ground squirrel (Ictidomys tridecemlineatus), Brian Lyons, Peter Karuso, Joanne Jamie, Mukoma F. Simpanya, Frank Giblin, and Roger J. W Truscott

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Negativity towards negative results: a discussion of the disconnect between scientific worth and scientific culture, Natalie Matosin, Elisabeth Frank, Martin Engel, Jeremy S. Lum, and Kelly Newell

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A novel population health data source to inform local planning: the SIMLR Study, Darren J. Mayne, Andrew Bonney, Bryan Jones, Lawrence Bott, Stephen Andersen, Peter Caputi, and Donald C. Iverson

Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease, Karen E. Murphy, Amanda M. Gysbers, Sarah K. Abbott, Nahid Tayebi, Woojin S. Kim, Ellen Sidransky, Anthony Cooper, Brett Garner, and Glenda M. Halliday

Post-testicular sperm maturation and identification of an epididymal protein in the Japanese quail (Coturnix coturnix japonica), Brett Nixon, Katherine A. Ewen, Klara M. Krivanek, John Clulow, Grahame Kidd, Heath Ecroyd, and Russell C. Jones

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Heme consumption reduces hepatic triglyceride and fatty acid accumulation in a rat model of NAFLD fed westernized diet, Soon Yew Tang, Irwin Kee M. Cheah, Pei Ern Ng, Aina Hoi, and Andrew M. Jenner

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Foods and food components in the Mediterranean diet: supporting overall effects, Linda Tapsell

Old proteins and the Achilles heel of mass spectrometry. The role of proteomics in the etiology of human cataract, Roger J. W Truscott and Michael Friedrich

Disease manifestations and pathogenic mechanisms of group A Streptococcus, Mark J. Walker, Timothy Barnett, Jason D. McArthur, Jason Cole, Christine Gillen, Anna Henningham, K S. Sriprakash, Martina L. Sanderson-Smith, and Victor Nizet

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Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates, Zhen Wang, Brian Lyons, Roger J. W Truscott, and Kevin L. Schey

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Central inflammation and leptin resistance are attenuated by ginsenoside Rb1 treatment in obese mice fed a high-fat diet, Yizhen Wu, Yinghua Yu, Alexander Szabo, Mei Han, and Xu-Feng Huang

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Hypothalamic ghrelin signalling mediates olanzapine-induced hyperphagia and weight gain in female rats, Qingsheng Zhang, Meng He, Chao Deng, Hongqin Wang, Jiamei Lian, and Xu-Feng Huang

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Olanzapine reduced brown adipose tissue thermogenesis and locomotor activity in female rats, Qingsheng Zhang, Jiamei Lian, Meng He, Chao Deng, Hongqin Wang, and Xu-Feng Huang

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Perturbation of neuronal cobalamin transport by lysosomal enzyme inhibition, Hua Zhao, Kalani Ruberu, Hongyun Li, and Brett Garner

Papers from 2013

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An Improved High-Throughput Lipid Extraction Method for the Analysis of Human Brain Lipids, Sarah K. Abbott, Andrew M. Jenner, Todd W. Mitchell, Simon H. Brown, Glenda M. Halliday, and Brett Garner

Global fatty acid composition is altered in Parkinson's disease anterior cingulate cortex, S K. Abbott, G M. Halliday, and B Garner

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Novel implications of Lingo-1 and its signalling partners in the Dorsolateral prefrontal cortex in schizophrenia, Jessica L. Andrews, Kelly A. Newell, Xu-Feng Huang, and Francesca Fernandez-Enright

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Structural and functional aspects of hetero-oligomers formed by the small heat shock proteins αB-crystallin and HSP27, J Andrew Aquilina, Sudichhya Shrestha, Amie M. Morris, and Heath Ecroyd

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Burden and support needs of carers of persons with borderline personality disorder: a systematic review, Rachel Bailey and Brin F. S Grenyer

Metacognitive Narrative Psychotherapy for people diagnosed with schizophrenia: an outline of a principle-based treatment manual, Rebecca Bargenquast and Robert Schweitzer

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Increased apolipoprotein-D dimer formation in Alzheimer's disease hippocampus is associated with lipid conjugated diene levels, Surabhi Bhatia, Andrew M. Jenner, Hongyun Li, Kalani Ruberu, Adena S. Spiro, Claire E. Shepherd, Jillian J. Kril, Nupur Kain, Anthony Don, and Brett Garner

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Men who have sex with men, infectious syphilis and HIV coinfection in inner Sydney: results of enhanced surveillance, Susan J. Botham, Kelly-Anne Ressler, Patrick Maywood, Kirsty G. Hope, Chris P. Bourne, Stephen J. Conaty, Mark J. Ferson, and Darren J. Mayne

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Cerium oxide nanoparticles: influence of the high-Z component revealed on radioresistant 9L cell survival under X-ray irradiation, Adam Briggs, stephanie corde, Sianne Oktaria, Ryan Brown, Anatoly B. Rosenfeld, Michael Lerch, Konstantin Konstantinov, and Moeava Tehei

A comparison of patient matched meibum and tear lipidomes, Simon H. Brown, Carolina M. E Kunnen, Eva Duchoslav, Naveen K. Dolla, Michael J. Kelso, Eric B. Papas, Percy Lazon de la Jara, Mark D.P Willcox, Stephen J. Blanksby, and Todd W. Mitchell

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Benefits, issues, and recommendations for personalized medicine in oncology in Canada, C Butts, S Kamel-Reid, G Batist, S Chia, C Blanke, M Moore, M B. Sawyer, C Desjardins, A Dubois, J Pun, K Bonter, and F D. Ashbury

Author reply, J Carmody, V Traynor, D Iverson, and E Marchetti

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Novel behavioural characteristics of the APPSwe/PS1ΔE9 transgenic mouse model of Alzheimer's disease, David Cheng, Warren Logge, Jac Kee Low, Brett Garner, and Tim Karl

Potential value and limitation of dual inhibitors of pi3k and mtor in the treatment of cancer, Jiezhong Chen

Recent advance in the studies of beta-glucans for cancer therapy, Jiezhong Chen

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The key regulatory roles of the PI3K/Akt signaling pathway in the functionalities of mesenchymal stem cells and applications in tissue regeneration, Jiezhong Chen, Ross Crawford, Chen Chen, and Yin Xiao

Vertical inhibition of the PI3K/Akt/mTOR pathway for the treatment of osteoarthritis, Jiezhong Chen, Ross Crawford, and Yin Xiao

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Applications of nanotechnology for melanoma treatment, diagnosis, and theranostics, Jiezhong Chen, Renfu Shao, Xu Dong Zhang, and Chen Chen

The application of fungal beta-glucans for the treatment of colon cancer, Jiezhong Chen, Xu Dong Zhang, and Zhengyi Jiang

Estrogen-induced cholestasis: pathogenesis and therapeutic implications, Jiezhong Chen, Kong-nan Zhao, and Guang Bin Liu

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Effects of antipsychotic medications on appetite, weight, and insulin resistance, Chao Deng

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Mapping the pathophysiology of schizophrenia: interactions between multiple cellular pathways, Chao Deng and Brian Dean

Improving services for people with personality disorders: views of experienced clinicians, Mahnaz Fanaian, Kate L. Lewis, and Brin F. S Grenyer

Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia, S Fillman, N Cloonan, V S. Catts, L C. Miller, J Wong, T Mccrossin, M Cairns, and C S. Weickert

An audit of vending machines in public places in regional NSW, Australia, V Flood, A Carrad, A Alshukri, J Louie, B Kelly, H Yeatman, and L Tapsell

An audit of vending machines in public places in regional NSW, Australia, V Flood, A Carrad, A Alshukri, J Louie, B Kelly, H Yeatman, and L Tapsell

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Laparoscopic management of an adnexal mass during the second trimester of pregnancy, C Georgiou

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Laparoscopy for theatre nurses, C Georgiou

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Pregnancies following the use of balloon tamponade technology in the previous pregnancy, C Georgiou

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Subsequent management of unsuccessful Fulshi clip tubal occlusion, C Georgiou

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Thrombus-like structures seen in the infundibular-pelvic ligament during the laparoscopic management of ovarian torsion, C Georgiou

Intercellular propagated misfolding of wild-type Cu-Zn superoxide dismutase, Leslie I. Grad, Justin J. Yerbury, Bradley J. Turner, Will C. Guest, Eddie Pokrishevsky, Megan A. O'Neill, Anat Yanai, Judith M. Silverman, Rafaa Zeineddine, Lisa Corcoran, Janet R. Kumita, Leila Luheshi, Masoud Yousefi, Bradley M. Coleman, Andrew F. Hill, Steven S. Plotkin, and Neil R. Cashman

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Neural correlates of successful encoding in schizophrenia: an event-related potential study, Amity Green, Paul Fitzgerald, Patricia T. Michie, Pradeep Nathan, and Rodney J. Croft

High-dose mushroom increases hepatic accumulation of triacylglycerol in rats fed with high-fat diet, D Handayani, B Meyer, J Chen, S Brown, T Mitchell, and Xu-Feng Huang

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Structure-informed design of an enzymatically inactive vaccine component for group A Streptococcus, Anna Henningham, Daniel J. Ericsson, Karla Langer, Lachlan W. Casey, Blagojce Jovcevski, G S. Chhatwal, John Andrew Aquilina, Michael R. Batzloff, Bostjan Kobe, and Mark J. Walker

Age-dependent racemization of serine residues in a human chaperone protein, Michelle Y. S Hooi, Mark J. Raftery, and Roger J. W Truscott

Accelerated aging of Asp 58 in aA crystallin and human cataract formation, Michelle Yu Sung Hooi, Mark Raftery, and Roger J. Truscott

Interconversion of the peptide isoforms of aspartate: Stability of isoaspartates, Michelle Yu Sung Hooi, Mark Raftery, and Roger J. Truscott

Association between DBH 19bp insertion/deletion polymorphism and cognition in first-episode schizophrenic patients, Li Hui, Xuan Zhang, Ya Qin Yu, Mei Han, Xu-Feng Huang, Da Chun Chen, Zhi Ren Wang, Wei Li Du, Chang Gui Kou, Qiong Yu, Thomas R. Kosten, and Xiang Yang Zhang

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The role of assertiveness on telephone crisis supporter well-being and service provision, Tara Hunt, Coralie Wilson, Peter Caputi, Alan Woodward, Grahame Gould, and Taneile Kitchingman

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In vivo pharmacological evaluations of novel olanzapine analogues in rats: a potential new avenue for the treatment of schizophrenia, Somayeh Jafari, Xu-Feng Huang, Jessica L. Andrews, and Francesca Fernandez-Enright

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Lipid Anti-Lipid Antibody Responses Correlate with Disease Activity in Systemic Lupus Erythematosus, Vojislav Jovanovic, Nurhuda Abdul Aziz, Yan Ting Lim, Amanda Ng Ai Poh, Sherlynn Jin Hui Chan, Eliza Ho Xin Pei, Fei Chuin Lew, Guanghou Shui, Andrew M. Jenner, Li Bowen, Eoin F. McKinney, Paul A. Lyons, Michael D. Kemeny, Kenneth G.C. Smith, Markus R. Wenk, and Paul A. MacAry

From the city to the bush: Increases in patient co-payments for medicines have impacted on medicine use across Australia, Anna Kemp, John Glover, David B. Preen, Max Bulsara, James Semmens, and Elizabeth Roughead

Impact of cost of medicines for chronic conditions on low income households in Australia, Anna Kemp, David B. Preen, John Glover, James Semmens, and Elizabeth E. Roughead

Myocardial infarction after intravitreal vascular endothelial growth factor inhibitors: A whole population study, Anna Kemp, David B. Preen, Nigel Morlet, Antony Clarke, Ian L. McAllister, Tom Briffa, Frank M. Sanfilippo, Jonathon Q. Ng, Charlotte McKnight, Wayne Reynolds, and Mark C. Gilles

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Ascertaining invasive breast cancer cases; the validity of administrative and self-reported data sources in Australia, Anna Kemp, David B. Preen, Christobel Saunders, C D'Arcy J. Holman, Max Bulsara, Kris Rogers, and Elizabeth E. Roughead

The effect of a western diet on the synthesis and metabolism of cholesterol in the brain, F Kreilaus and A M. Jenner

The MASCC/ISOO Mucositis Guidelines: dissemination and clinical impact, Rajesh V. Lalla and Fredrick D. Ashbury

Mammalian expression systems and transfection techniques, Daunia Laurenti and Lezanne Ooi

Mammalian expression systems and transfection techniques, Daunia Laurenti and Lezanne Ooi

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Effects of olanzapine and betahistine co-treatment on serotonin transporter, 5-HT2A and dopamine D2 receptor binding density, Jiamei Lian, Xu-Feng Huang, Nagesh Pai, and Chao Deng

Deletion of ABCA7 increases cerebral amyloid-β deposition in the J20 mouse model of Alzheimer's disease, H Li, W S. Kim, K Ruberu, S Chan, D Elliott, J K. Low, D Cheng, T Karl, and B Garner

Whole grains, type 2 diabetes, coronary heart disease, and hypertension: links to the aleurone preferred over indigestible fiber, Stephen Lillioja; Andrew L. Neal; Linda Tapsell; and David R. Jacobs, Jr

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Reciprocity as deliberative capacity: lessons from a citizens deliberation on carbon pricing mechanisms in Australia, Alex Y. Lo, Kim S. Alexander, Wendy Proctor, and Anthony Ryan

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Sleep-wake behaviour and the EEG in altered states of consciousness, Sarah P. Loughran, Sabine Regel, Lilith Buetler, Martin Wieser, Robert Riener, and Peter Achermann

Age-dependent modification of proteins: N-terminal racemization, Brian Lyons, A H. Kwan, Joanne Jamie, and Roger J.W Truscott

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An objective index of walkability for research and planning in the Sydney Metropolitan Region of New South Wales, Australia: an ecological study, Darren J. Mayne, Geoffrey Morgan, Alan Willmore, Nectarios Rose, Bin Jalaludin, Hilary Bambrick, and Adrian Bauman

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Analysis of the psychological impact of a vascular risk factor intervention: results from a cluster randomized controlled trial in Australian general practice, Suzanne Helen Mckenzie, Upali W. Jayasinghe, Mahnaz Fanaian, Megan Passey, and Mark Fort Harris

Molecular markers for the study of streptococcal epidemiology, David J. McMillan, Martina L. Sanderson-Smith, Pierre Robert Smeesters, and Kadaba S. Sriprakash

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Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding, M K. Montgomery, N L. Hallahan, S H. Brown, M Liu, T W. Mitchell, G J. Cooney, and N Turner

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Evaluating success in public Health advocacy strategies, Michael Moore, Heather Yeatman, and Christina Pollard

Metabotropic glutamate receptor 5 in schizophrenia: emerging evidence for the development of antipsychotic drugs, Kelly A. Newell

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Proenergetic effects of resveratrol in the murine neuronal cell line Neuro2a, Nhu T.Q Nguyen, Lezanne Ooi, Sabine C. Piller, and Gerald Munch

Development and evaluation of the REACH (Recognise End of life And Care Holistically) out in Dementia toolkit, J. Potter, Ramesh Fernando, and Nancy Humpel

Categorising foods in terms of nutrient content, Yasmine Probst, Linda Tapsell, Rebecca Thorne, and Jane O'Shea

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A key role for the urokinase plasminogen activator (uPA) in invasive Group A streptococcal infection, Martina L. Sanderson-Smith, Yueling Zhang, Diane Ly, Deborah Donahue, Andrew Hollands, Victor Nizet, Marie Ranson, Victoria A. Ploplis, Mark J. Walker, and Francis J. Castellino

Improved GC-MS methods for analysis of homocysteine, methionine and methylmalonate in cultured cells, A S. Spiro, A M. Jenner, and B Garner