Title

Cognitive and neural processes in non-clinical auditory hallucinations

RIS ID

31089

Publication Details

Barkus, E, Stirling, J, Hopkins, R, Mckie, S & Lewis, S, Cognitive and neural processes in non-clinical auditory hallucinations, British Journal of Psychiatry, 191(S51), 2007, s76-81.

Abstract

BACKGROUND: The nosological status of auditory hallucinations in non-clinical samples is unclear. AIMS: To investigate the functional neural basis of non-clinical hallucinations. METHOD: After selection from 1206 people, 68 participants of high, medium and low hallucination proneness completed a task designed to elicit verbal hallucinatory phenomena under conditions of stimulus degradation. Eight subjects who reported hearing a voice when none was present repeated the task during functional imaging. RESULTS: During the signal detection task, the high hallucination-prone participants reported a voice to be present when it was not (false alarms) significantly more often than the average or low participants (P<0.03, d.f.=2). On functional magnetic resonance imaging, patterns of activation during these false alarms showed activation in the superior and middle temporal cortex (P<0.001). CONCLUSIONS: Auditory hallucinatory experiences reported in non-clinical samples appear to be mediated by similar patterns of cerebral activation as found during hallucinations in schizophrenia.

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Link to publisher version (DOI)

http://dx.doi.org/10.1192/bjp.191.51.s76