Okely, Anthony D.; Collins, Clare E.; Morgan, Philip J.; Jones, Rachel A.; Warren, Janet M.; Cliff, Dylan P.; Burrows, Tracy L.; Colyvas, Kim; Steele, Julie R.; and Baur, Louise A., 2010, Multi-site randomized controlled trial of a child-centered physical activity program, a parent-centered dietary-modification program, or both in overweight children: The HIKCUPS study, The Journal of Pediatrics, 157(3), 388-394.
Overweight and obesity in childhood have been described as a global epidemic, with 10% of the world’s children currently affected and the prevalence increasing. Obesity in children is associated with a range of immediate and longterm comorbidities. The development and implementation of prevention and treatment strategies presents a formidable challenge for researchers and practitioners. This challenge has been articulated in recent systematic reviews of treatment interventions, which showed poor long-term and, at best, modest short-term success.5-7 Many of the studies had methodologic limitations such as small sample sizes, high attrition rates, limited outcome data, no intention-to-treat analyses, and insufficient follow-up periods. Furthermore, many were highly resource-intensive and performed in tertiary environments, limiting their potential reach and subsequent impact on regional/national child obesity prevalences.