RIS ID

115106

Publication Details

Oktaria, S., Lerch, M. L. F., Rosenfeld, A. B., Tehei, M. & Corde, S. (2017). In vitro investigation of the dose-rate effect on the biological effectiveness of megavoltage X-ray radiation doses. Applied Radiation and Isotopes, 128 114-119.

Abstract

Radiation therapy is rapidly evolving toward the delivery of higher dose rates to improve cancer treatment. In vitro experiments were performed to investigate the response of 9L and MCF-7 cancer cell lines, exposed to 10 MV X-ray radiations. Up to 8 Gy was delivered at a dose-rate of 50 cGy/min compared to 5 Gy/min. The data obtained emphasizes the importance of taking into account not only the physical, but also the radiobiological parameters, when planning a particular cancer treatment.

Grant Number

NHMRC/1084994

Available for download on Friday, July 06, 2018

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