Encapsulation of L-Histidine amino acid inside single-walled carbon nanotubes

Authors

Hakim Abdul Al Garalleh, University of WollongongFollow
Ngamta Thamwattana, University of WollongongFollow
Barry J. Cox, University of WollongongFollow
James M. Hill, University of WollongongFollow

RIS ID

107931

Publication Details

Al Garalleh, H., Thamwattana, N., Cox, B. J. & Hill, J. M. (2016). Encapsulation of L-Histidine amino acid inside single-walled carbon nanotubes. Journal of Biomaterials and Tissue Engineering, 6 (5), 362-369.

Abstract

Carbon nanotubes have attracted considerable interest for their use as carriers of drugs across biological barriers. In this work, we investigate the encapsulation of L-Histidine amino acid inside a single-walled carbon nanotube, and determine the resultant interaction energy for various sizes of the nanotubes. In our model, the L-Histidine amino acid is accounted for in four parts; the inner ring group, the half outer group, the linear part and the cylinder group, all interacting with a single-walled carbon nanotube. We calculate the acceptance and suction energies which depend on the radius r of the carbon nanotube and the orientation angle Ø that the amino acid makes with the central axis of the nanotube. Our results indicate the acceptance of the L-Histidine amino acid into carbon nanotubes of r >3.7 Å, which is in good agreement with other recent studies.