Title

BrachyView: multiple seed position reconstruction and comparison with CT post-implant dosimetry

RIS ID

107111

Publication Details

Alnaghy, S., Loo, K. J., Cutajar, D. L., Jalayer, M., Tenconi, C., Favoino, M., Rietti, R., Tartaglia, M., Carriero, F., Safavi-Naeini, M., Bucci, J., Jakubek, J., Pospisil, S., Zaider, M., Lerch, M. L. F., Rosenfeld, A. B. & Petasecca, M. (2016). BrachyView: multiple seed position reconstruction and comparison with CT post-implant dosimetry. Journal of Instrumentation, 11 (5), P05002-1-P05002-16.

Abstract

BrachyView is a novel in-body imaging system utilising high-resolution pixelated silicon detectors (Timepix) and a pinhole collimator for brachytherapy source localisation. Recent studies have investigated various options for real-time intraoperative dynamic dose treatment planning to increase the quality of implants. In a previous proof-of-concept study, the justification of the pinhole concept was shown, allowing for the next step whereby multiple active seeds are implanted into a PMMA phantom to simulate a more realistic clinical scenario. In this study, 20 seeds were implanted and imaged using a lead pinhole of 400 μ m diameter. BrachyView was able to resolve the seed positions within 1–2 mm of expected positions, which was verified by co-registering with a full clinical post-implant CT scan.

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Link to publisher version (DOI)

http://dx.doi.org/10.1088/1748-0221/11/05/P05002