MR imaging-guided partial volume correction of PET data in PET/MR imaging

Authors

Kjell Erlandsson, University College London
John Dickson, University College London
Simon Arridge, University College London
David Atkinson, University College London
Sebastien Ourselin, University College London
Brian F. Hutton, University College London, University of Wollongong

RIS ID

105927

Publication Details

Erlandsson, K., Dickson, J., Arridge, S., Atkinson, D., Ourselin, S. & Hutton, B. F. (2016). MR imaging-guided partial volume correction of PET data in PET/MR imaging. PET Clinics, 11 (2), 161-177.

Abstract

Partial volume effects are caused by the limited spatial resolution of the PET system. There is increasing evidence that partial volume correction (PVC) is necessary to guarantee quantitative accuracy in PET; however, there is reluctance to apply PVC routinely in clinical practice, partly because of uncertainty regarding the method of choice. To perform accurate PVC, it is necessary to introduce information from high-resolution anatomic images, such as MR imaging. All the methods rely on accurate coregistration between the anatomic image and the PET image. PET/MR imaging offers clear advantages for PVC and can help alleviate the image registration issues.