Title

Physical-chemical properties of cross-linked chitosan electrospun fiber mats

RIS ID

99219

Publication Details

Sencadas, V., Correia, D. M., Ribeiro, C., Moreira, S., Botelho, G., Gomez Ribelles, J. L. & Lanceros-Méndez, S. (2012). Physical-chemical properties of cross-linked chitosan electrospun fiber mats. Polymer Testing, 31 (8), 1062-1069.

Abstract

Chitosan fiber mats were successfully processed by electrospinning. The as-spun fiber mats were neutralized with ethanol and cross-linked with glutaraldehyde. A decrease of the fiber average diameter from 243 ± 43 nm down to 215.53 nm was observed for the neutralized and cross-linking chitosan membrane. It was found that the processing conditions do not alter the initial deacetylation degree of the polymer. Polymer crystallinity index showed a decrease from 61% for the Protasan material down to 17% for the cross-linking fiber mats. A swelling index up to 1000% was observed for the cross-linked samples. Preliminary MC-3T3-E1cell culture results showed good cell adhesion and proliferation in the cross-linked chitosan fiber mats.

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