Piezoelectric poly(vinylidene fluoride) microstructure and poling state in active tissue engineering

Authors

Clarisse Ribeiro, University of Minho
Daniela M. Correia, University of Minho
S Ribeiro, University of Minho
Vitor Sencadas, University of WollongongFollow
Gabriela Botelho, University of Minho
Senentxu Lanceros-Méndez, University of Minho

RIS ID

99097

Publication Details

Ribeiro, C., Correia, D. M., Ribeiro, S., Sencadas, V., Botelho, G. & Lanceros-Méndez, S. (2015). Piezoelectric poly(vinylidene fluoride) microstructure and poling state in active tissue engineering. Engineering in Life Sciences, 15 351-356.

Abstract

Tissue engineering strategies rely on suitable membranes and scaffolds, providing the necessary physicochemical stimuli to specific cells. This review summarizes the main results on piezoelectric polymers, in particular poly(vinylidene fluoride), for muscle and bone cell culture. Further, the relevance of polymer microstructure and surface charge on cell response is demonstrated. Together with the necessary biochemical cues, the proper design of piezoelectric polymers can open the way to novel and more reliable tissue engineering strategies for cells in which electromechanical stimuli are present in their environment.