BrachyView: tomographic reconstruction using Timepix detectors in post-implant dosimetry checks for permanent prostate brachytherapy implants

Authors

Kevin Loo, University of WollongongFollow
Marco Petasecca, University of WollongongFollow
M Safavi-Naeini, University of WollongongFollow
Zhangbo Han, University of WollongongFollow
Michael L. F Lerch, University of WollongongFollow
Joseph A. Bucci, St George Cancer Care Centre
Jan Jakubek, Czech Technical University
Jan Zemlicka, Czech Technical University
Steven R. Meikle, University of Sydney
Marco Zaider, Memorial Sloan Kettering Cancer Center USA
Anatoly B. Rosenfeld, University of WollongongFollow

RIS ID

91944

Publication Details

Loo, K. J., Petasecca, M., Safavi-Naeini, M., Han, Z., Lerch, M., Bucci, J., Jakubek, J., Zemlicka, J., Meikle, S., Zaider, M. & Rosenfeld, A. (2013). BrachyView: tomographic reconstruction using Timepix detectors in post-implant dosimetry checks for permanent prostate brachytherapy implants. IEEE Nuclear Science Symposium Conference Record (pp. 1-3). United States: IEEE.

Abstract

Computed tomography imaging is a mandatory part of the permanent prostate brachytherapy procedure. It is used as a post-implant dosimetric check to evaluate the quality of the implant. It is proposed that by using a novel assembly of multiple high-resolution pixelated detectors Timepix, an in-body probe can be used as a multi-modality imaging device. Preliminary phantom studies of a PMMA prostate phantom with implanted dummy I-125 seeds (Oncura Model 6711) have shown a qualitative confirmation of three-dimensional tomographic reconstruction from limited angles and limited field of view based on iterative reconstruction algorithms.