The evaluation of distortion diagnosis using Wavelet function for Electrocardiogram (ECG), Electroen- cephalogram (EEG) and Phonocardiography (PCG) is not novel. However, some of the technological and economic issues remain challenging. The work in this paper is focusing on the reduction of the noise inter- ferences and analyzes different kinds of ECG signals. Furthermore, a physiological monitoring system with a programming model for the filtration of ECG is presented. Kaiser based Finite Impulse Response (FIR) filter is used for noise reduction and identifica- tion of R peaks based on Peak Detection Algorithm (PDA). Two approaches are implemented for detect- ing the R peaks; Amplitude Threshold Value (ATV) and Peak Prediction Technique (PPT). Daubechies wavelet transform is applied to analyze the ECG of driver under stress, arrhythmia and sudden cardiac arrest signals. From the obtained results, it was found that the PPT is an effective and efficient technique in detecting the R peaks compared to ATV.