Title

Additional support for linkage of schizophrenia and bipolar disorder to chromosome 3q29

Document Type

Journal Article

Publication Details

Schosser, A., Fuchs, K., Scharl, T., Leisch, F., Bailer, U., Kasper, S., Sieghart, W., Hornik, K. & Aschauer, H. N. (2007). Additional support for linkage of schizophrenia and bipolar disorder to chromosome 3q29. European Neuropsychopharmacology, 17 (6-7), 501-505.

Abstract

After publishing a genome scan and follow-up fine mapping, suggesting schizophreniaand bipolar disorder linkage to chromosome 3q29, we now genotyped 11 additional SNPs (singlenucleotide polymorphisms), in order to narrow down a potential candidate region. Linkage wasperformed using the GENEHUNTER program version 2.1r3. A NPL score Zall of 3.891 (p=0.000156)was observed with SNP rs225. In short, we found significant linkage scores most telomeric onchromosome 3q29, spanning 3.46 Mbp (7 SNPs).

RIS ID

22670

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Link to publisher version (DOI)

http://dx.doi.org/10.1016/j.euroneuro.2007.01.004