Title

Development of hybrid systems for cell-mediated muscle regeneration: advanced electromaterials and wet-spun biodegradable fibers

RIS ID

32607

Publication Details

Razal, J. M., Kita, M., Quigley, A. F., Kennedy, E., Moulton, S. E., Wallace, G. G., Clark, G. M. & Kapsa, R. M. (2009). Development of hybrid systems for cell-mediated muscle regeneration: advanced electromaterials and wet-spun biodegradable fibers. In 6th Australasian Gene Therapy Society Meeting, 29 Apr- 1 May, Sydney. Journal of Gene Medicine, 11 (9), 847-847.

Abstract

In myo-dystrophic processes such as Duchenne muscular dystrophy (DMD), onset of disease pathology is associated with significant loss of regenerative precursor cells. In the face of such significant cell loss, it is likely that even with the rectification of the genetic defect, some measure of cell replacement therapy will still be required to replace the large amounts muscle tissues and precursors lost during the dystrophic process.

Grant Number

ARC/DP0987503