Centrifugal microfluidics for cell analysis

Authors

Robert Burger, Dublin City University
Daniel Kirby, Dublin City University
Macdara Glynn, Dublin City University
Charles E Nwankire, Dublin City University
Mary O'Sullivan, University of Limerick
Jonathan Siegrist, Dublin City University
David Kinahan, Dublin City University
Gerson Aguirre, Dublin City University
Gregor Kijanka, Dublin City University
Robert A. Gorkin III, Dublin City UniversityFollow
Jens Ducree, Dublin City University

RIS ID

78653

Publication Details

Burger, R., Kirby, D., Glynn, M., Nwankire, C., O'Sullivan, M., Siegrist, J., Kinahan, D., Aguirre, G., Kijanka, G., Gorkin III, R. A. & Ducree, J. (2012). Centrifugal microfluidics for cell analysis. Current Opinion in Chemical Biology, 16 409-414.

Abstract

Over the past two decades, centrifugal microfluidic systems have successfully demonstrated their capability for robust, high-performance liquid handling to enable modular, multipurpose lab-on-a-chip platforms for a wide range of lifescience applications. Beyond the handling of homogeneous liquids, the unique, rotationally controlled centrifugal actuation has proven to be specifically advantageous for performing cell and particle handling and assays. In this review we discuss technologies to implement two important steps for cell handling, namely separation and capturing/counting.