pH-responsive Fe(III)-gallic acid nanoparticles for in vivo photoacoustic imaging-guided photothermal therapy

Authors

Jianfeng Zeng, Soochow University, China
Ming Cheng, Soochow University, China
Yong Wang, Soochow University, China
Ling Wen, Soochow University, China
Ling Chen, Soochow University, China
Zhen Li, University of WollongongFollow
Yongyou Wu, Soochow University, China
Mingyuan Gao, Beijing National Laboratory For Molecular Sciences
Zhifang Chai, Soochow University, China

RIS ID

105830

Publication Details

Zeng, J., Cheng, M., Wang, Y., Wen, L., Chen, L., Li, Z., Wu, Y., Gao, M. & Chai, Z. (2016). pH-responsive Fe(III)-gallic acid nanoparticles for in vivo photoacoustic imaging-guided photothermal therapy. Advanced Healthcare Materials, 5 (7), 772-780.

Abstract

pH-responsive biocompatible Fe(III)-gallic acid nanoparticles with strong near-infrared absorbance are very stable in mild acidic conditions, but easily decomposed in neutral conditions, which enables the nanoparticles to be stable in a tumor and easily metabolized in other organs, thus providing a safe nanoplatform for in vivo photoacoustic imaging/photothermal therapy theranostic applications.