An electrospun strong PCL/PU composite vascular graft with mechanical anisotropy and cyclic stability

Authors

Fengyun Guo, Beihang University
Nu Wang, University of Wollongong
Li Wang, Chinese Academy Of Sciences, Beijing, China
Lanlan Hou, Beihang University
Lan Ma, Beihang University
Jing Liu, University of Science and Technology of China
Yuee Chen, Beihang University
Bingbing Fan, Beihang University
Yong Zhao, University of WollongongFollow

RIS ID

98654

Publication Details

Guo, F., Wang, N., Wang, L., Hou, L., Ma, L., Liu, J., Chen, Y., Fan, B. & Zhao, Y. (2015). An electrospun strong PCL/PU composite vascular graft with mechanical anisotropy and cyclic stability. Journal of Materials Chemistry A, 3 (9), 4782-4787.

Abstract

A strong PCL/PU (polycaprolactone/polyurethane) vascular graft was fabricated using electrospinning. By regulating the content of PCL, the composite scaffolds show an obvious mechanical enhancement with strength up to 69.95 MPa. Furthermore, the scaffolds exhibit high porosity, mechanical anisotropy, cell compatibility and cycle performance, which are important for tissue engineering applications.